Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957471 | 0.85 | CTDSP1 (0.58) | PLAUCTDSP1ALDH1A1KDM4EENPP2 | |
| SCHEMBL29955724 | 0.80 | PLAU (0.42) | PLAUALDH1A1KDM4EENPP2HSD17B10 | |
| SCHEMBL4794960 | 0.78 | TLR8 (0.46) | ENPP2CYP3A4CYP1A2 | |
| SCHEMBL29957465 | 0.78 | TLR8 (0.46) | ENPP2CYP3A4CYP1A2 | |
| SCHEMBL3186823 | 0.78 | CYP1A2 (0.59) | ALDH1A1KDM4EHSD17B10TDP1CA2 | |
| SCHEMBL29091226 | 0.77 | CYP1A2 (0.41) | PLAUALDH1A1KDM4EENPP2HSD17B10 | |
| SCHEMBL24794301 | 0.77 | CYP2A6 (0.43) | ENPP2TSHRHTTCYP1A2 | |
| SCHEMBL16553301 | 0.77 | CYP2A6 (0.43) | PLAUALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL29953232 | 0.77 | CYP1A2 (0.43) | ENPP2CYP1A2 | |
| SCHEMBL17728138 | 0.77 | CYP1A2 (0.43) | ENPP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |