Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033616 | 1.00 | KLKB1 (0.34) | KLKB1METTL3CNR1 | |
| SCHEMBL27033578 | 0.95 | KLKB1 (0.34) | KLKB1METTL3CNR1 | |
| SCHEMBL29958101 | 0.95 | KLKB1 (0.34) | KLKB1METTL3CNR1 | |
| SCHEMBL27033429 | 0.94 | KLKB1 (0.37) | KLKB1METTL3 | |
| SCHEMBL29958081 | 0.94 | KLKB1 (0.37) | KLKB1METTL3 | |
| SCHEMBL29958120 | 0.91 | KLKB1 (0.33) | KLKB1METTL3CNR1 | |
| SCHEMBL27033542 | 0.91 | KLKB1 (0.33) | KLKB1METTL3CNR1 | |
| SCHEMBL29958121 | 0.91 | KLKB1 (0.35) | KLKB1METTL3CNR1 | |
| SCHEMBL29957797 | 0.90 | KLKB1 (0.33) | KLKB1METTL3CNR1 | |
| SCHEMBL27033661 | 0.90 | KLKB1 (0.33) | KLKB1METTL3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308228-A1 | PLASMA KALLIKREIN INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022197756-A1 | PLASMA KALLIKREIN INHIBITORS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |