Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 10/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.72 |
| ▸ | BRAF | P15056 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.72 |
| ▸ | RAF1 | P04049 | 2/20 | 0.72 |
| ▸ | KDR | P35968 | 2/20 | 0.72 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.72 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.72 |
| ▸ | NEK2 | P51955 | 2/20 | 0.72 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.72 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.72 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.72 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.72 |
| ▸ | NEK11 | Q8NG66 | 2/20 | 0.72 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.72 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
| ▸ | KRAS | P01116 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299171 | 0.88 | CYP2C19 (0.74) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL299109 | 0.87 | CYP2C19 (0.75) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL299516 | 0.86 | CYP2C19 (0.86) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL293377 | 0.86 | CYP2C19 (1.00) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL2016823 | 0.86 | CYP2C19 (0.74) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL299286 | 0.86 | CYP2C19 (0.78) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL2017139 | 0.86 | CYP2C19 (0.76) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL298431 | 0.86 | CYP2C19 (0.80) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL855840 | 0.86 | BRAF (0.87) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 | |
| SCHEMBL29898578 | 0.86 | BRAF (0.87) | CYP2C19CYP2C9BRAFCYP3A4RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427433-A1 | SOLID FORMS OF SULFONAMIDES AND AMINO ACIDS | Plexxikon, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |