Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23592761 | 1.00 | KDM1A (0.36) | KDM1AOGAPIK3CDPIK3R1PIK3CA | |
| SCHEMBL25063615 | 0.81 | KDM1A (0.38) | KDM1AOGAPIK3CDPIK3R1PIK3CA | |
| SCHEMBL29195182 | 0.80 | EGFR (0.42) | KDM1AOGAPTPN11MKNK1MKNK2 | |
| SCHEMBL29195158 | 0.80 | EGFR (0.42) | KDM1AOGAPTPN11MKNK1MKNK2 | |
| SCHEMBL15740518 | 0.80 | EGFR (0.42) | KDM1AOGAPTPN11MKNK1MKNK2 | |
| SCHEMBL15740521 | 0.80 | EGFR (0.42) | KDM1AOGAPTPN11MKNK1MKNK2 | |
| SCHEMBL19015576 | 0.80 | EGFR (0.42) | KDM1AOGAPTPN11MKNK1MKNK2 | |
| SCHEMBL30848834 | 0.80 | EGFR (0.42) | KDM1AOGAPTPN11MKNK1MKNK2 | |
| SCHEMBL15749462 | 0.80 | EGFR (0.42) | KDM1AOGAPTPN11MKNK1MKNK2 | |
| SCHEMBL23593463 | 0.77 | PTPN11 (0.48) | KDM1AOGAPIK3CDPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135642-B | Inhibitors of EGFR mutant forms | 缆图药品公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4081515-A1 | INHIBITORS OF MUTANT FORMS OF EGFR | Blueprint Medicines Corporation (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-115135642-A | Inhibitors of mutant forms of EGFR | 缆图药品公司 | 2022-09-30 | — | — | CN | disclosed |