SCHEMBL29959776

SCHEMBL29959776

O=c1[nH]c2c(S(=O)(=O)c3ccc4[nH]cnc4c3)cccc2c(=O)n1O

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FEN1 P39748 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18687693 1.00 FEN1 (0.86) FEN1
SCHEMBL22272265 0.82 FEN1 (0.62) FEN1
SCHEMBL29960097 0.78 FEN1 (1.00) FEN1
SCHEMBL18670490 0.78 FEN1 (1.00) FEN1
SCHEMBL18688345 0.77 FEN1 (1.00) FEN1
SCHEMBL18670337 0.77 FEN1 (1.00) FEN1
SCHEMBL29959655 0.77 FEN1 (1.00) FEN1
SCHEMBL18670578 0.77 FEN1 (1.00) FEN1
SCHEMBL18687690 0.77 FEN1 (1.00) FEN1
SCHEMBL18670302 0.77 FEN1 (1.00) FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430978-B 3-hydroxy-quinazoline-2, 4-dione derivatives and their use as nuclease modulators 路德维格癌症研究所有限责任公司 2022-11-22 — — CN disclosed
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