SCHEMBL29959862

SCHEMBL29959862

CC(C)n1ccc2ccc(S(=O)(=O)c3ccc(Cl)c4c(=O)n(O)c(=O)[nH]c34)cc21

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FEN1 P39748 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18670552 1.00 FEN1 (0.61) FEN1
SCHEMBL29959774 0.87 FEN1 (0.64) FEN1
SCHEMBL22262183 0.87 FEN1 (0.64) FEN1
SCHEMBL22262137 0.87 FEN1 (0.59) FEN1
SCHEMBL29960088 0.87 FEN1 (0.59) FEN1
SCHEMBL18670413 0.83 FEN1 (0.62) FEN1
SCHEMBL22262115 0.83 FEN1 (0.59) FEN1
SCHEMBL18670492 0.83 FEN1 (0.59) FEN1
SCHEMBL29959998 0.83 FEN1 (0.62) FEN1
SCHEMBL29960133 0.83 FEN1 (0.59) FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430978-B 3-hydroxy-quinazoline-2, 4-dione derivatives and their use as nuclease modulators 路德维格癌症研究所有限责任公司 2022-11-22 — — CN disclosed
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