SCHEMBL29959871

SCHEMBL29959871

CC(C)n1ncc2ccc(S(=O)(=O)c3ccc(Cl)c4c(=O)n(O)c(=O)[nH]c34)cc21

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FEN1 P39748 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18670492 1.00 FEN1 (0.59) FEN1
SCHEMBL18670503 0.88 FEN1 (0.62) FEN1
SCHEMBL29960047 0.88 FEN1 (0.62) FEN1
SCHEMBL18670501 0.88 FEN1 (0.57) FEN1
SCHEMBL29959876 0.88 FEN1 (0.57) FEN1
SCHEMBL22262149 0.84 FEN1 (0.57) FEN1
SCHEMBL29959854 0.84 FEN1 (0.57) FEN1
SCHEMBL18670264 0.84 FEN1 (0.60) FEN1
SCHEMBL29959907 0.84 FEN1 (0.60) FEN1
SCHEMBL18670552 0.83 FEN1 (0.61) FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430978-B 3-hydroxy-quinazoline-2, 4-dione derivatives and their use as nuclease modulators 路德维格癌症研究所有限责任公司 2022-11-22 — — CN disclosed
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