SCHEMBL29959954

SCHEMBL29959954

O=c1[nH]c2c(S(=O)(=O)c3ccc4ccn(C5CC5)c4c3)ccc(Cl)c2c(=O)n1O

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FEN1 P39748 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18670512 1.00 FEN1 (0.58) FEN1
SCHEMBL18670277 0.96 FEN1 (0.56) FEN1
SCHEMBL18670493 0.96 FEN1 (0.56) FEN1
SCHEMBL29959967 0.96 FEN1 (0.56) FEN1
SCHEMBL29959970 0.96 FEN1 (0.56) FEN1
SCHEMBL18670313 0.92 FEN1 (0.55) FEN1
SCHEMBL29960066 0.92 FEN1 (0.55) FEN1
SCHEMBL22262126 0.91 FEN1 (0.56) FEN1
SCHEMBL22262125 0.91 FEN1 (0.56) FEN1
SCHEMBL22262145 0.91 FEN1 (0.56) FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430978-B 3-hydroxy-quinazoline-2, 4-dione derivatives and their use as nuclease modulators 路德维格癌症研究所有限责任公司 2022-11-22 — — CN disclosed
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