SCHEMBL29960057

SCHEMBL29960057

Cn1cnc2cc(S(=O)(=O)c3ccc(Cl)c4c(=O)n(O)c(=O)[nH]c34)ccc21

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FEN1 P39748 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22262147 1.00 FEN1 (0.62) FEN1
SCHEMBL22262161 0.92 FEN1 (0.62) FEN1
SCHEMBL29960106 0.92 FEN1 (0.62) FEN1
SCHEMBL18670589 0.83 FEN1 (0.65) FEN1
SCHEMBL29960921 0.83 FEN1 (0.65) FEN1
SCHEMBL22262297 0.82 FEN1 (0.64) FEN1
SCHEMBL29960419 0.82 FEN1 (0.64) FEN1
SCHEMBL18670511 0.81 FEN1 (0.76) FEN1
SCHEMBL29960068 0.81 FEN1 (0.76) FEN1
SCHEMBL18670366 0.81 FEN1 (0.62) FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430978-B 3-hydroxy-quinazoline-2, 4-dione derivatives and their use as nuclease modulators 路德维格癌症研究所有限责任公司 2022-11-22 — — CN disclosed
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