SCHEMBL29960166

SCHEMBL29960166

CC1CCCN(c2ncc(Cl)c(Nc3ccc4c(c3)n(CCC(C)(C)O)c(=O)n4C)n2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ BCL6 P41182 20/20 1.00
▸ NCOR2 Q9Y618 6/20 1.00
▸ ADRB3 P13945 1/20 0.75
▸ HTR1D P28221 1/20 0.75
▸ ADORA1 P30542 1/20 0.75
▸ OPRM1 P35372 1/20 0.75
▸ SLC6A3 Q01959 1/20 0.75
▸ TMEM97 Q5BJF2 1/20 0.75
▸ HRH3 Q9Y5N1 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20568909 1.00 BCL6 (1.00) BCL6NCOR2ADRB3HTR1DADORA1
Formic Acid SCHEMBL26982943 0.97 BCL6 (0.94) BCL6NCOR2ADRB3HTR1DADORA1
SCHEMBL23357506 0.92 BCL6 (0.90) BCL6NCOR2ADRB3HTR1DADORA1
SCHEMBL30745266 0.92 BCL6 (0.90) BCL6NCOR2ADRB3HTR1DADORA1
SCHEMBL20569708 0.91 BCL6 (1.00) BCL6NCOR2ADRB3HTR1DADORA1
SCHEMBL29960375 0.91 BCL6 (1.00) BCL6NCOR2ADRB3HTR1DADORA1
SCHEMBL29960188 0.91 BCL6 (1.00) BCL6NCOR2ADRB3HTR1DADORA1
SCHEMBL23357486 0.91 BCL6 (1.00) BCL6NCOR2ADRB3HTR1DADORA1
SCHEMBL23267548 0.91 BCL6 (0.84) BCL6NCOR2ADRB3HTR1DADORA1
SCHEMBL20569093 0.90 BCL6 (1.00) BCL6NCOR2ADRB3HTR1DADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630291-B9 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-05-29 — — EP claimed
CN-111163839-B Benzimidazolone-derived BCL6 inhibitors 癌症研究科技有限公司 2024-05-28 — — CN claimed
EP-3630291-B1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-01-10 — — EP claimed
EP-4061834-A1 CHEMICALLY INDUCIBLE POLYPEPTIDE POLYMERIZATION Dana-Farber Cancer Institute, Inc. (US) 2022-09-28 — — EP claimed
CN-118561812-A Benzimidazolone-derived BCL6 inhibitors 癌症研究科技有限公司 2024-08-30 — — CN disclosed
EP-3630291-B9 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-05-29 — — EP disclosed
EP-4374858-A2 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 Cancer Research Technology Limited (GB) 2024-05-29 — — EP disclosed
CN-111163839-B Benzimidazolone-derived BCL6 inhibitors 癌症研究科技有限公司 2024-05-28 — — CN disclosed
EP-3630291-B1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-01-10 — — EP disclosed
EP-4061834-A1 CHEMICALLY INDUCIBLE POLYPEPTIDE POLYMERIZATION Dana-Farber Cancer Institute, Inc. (US) 2022-09-28 — — EP disclosed
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