⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23498086 | 1.00 | — | — | |
| SCHEMBL14709163 | 0.87 | — | — | |
| SCHEMBL12902285 | 0.87 | — | — | |
| SCHEMBL12940551 | 0.87 | — | — | |
| SCHEMBL14382236 | 0.87 | — | — | |
| SCHEMBL12902300 | 0.87 | — | — | |
| SCHEMBL14709022 | 0.87 | — | — | |
| SCHEMBL28230372 | 0.86 | — | — | |
| SCHEMBL9293838 | 0.83 | — | — | |
| SCHEMBL18026265 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10765648-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2020-09-08 | — | — | US | disclosed |
| EP-2785683-B1 | INKT CELL MODULATORS AND METHODS OF USING THE SAME | LUDWIG INST FOR CANCER RES LTD (CH) | 2020-02-05 | — | — | EP | disclosed |
| US-10314796-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2019-06-11 | — | — | US | disclosed |
| US-20170368002-A1 | INKT CELL MODULATORS AND METHODS OF USING THE SAME | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2017-12-28 | — | — | US | disclosed |
| US-9700532-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2017-07-11 | — | — | US | disclosed |
| US-9700532-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2017-07-11 | — | — | US | disclosed |
| US-20160361280-A1 | INKT CELL MODULATORS AND METHODS OF USING THE SAME | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2016-12-15 | — | — | US | disclosed |
| US-20160361280-A1 | INKT CELL MODULATORS AND METHODS OF USING THE SAME | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2016-12-15 | — | — | US | disclosed |
| US-9365496-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2016-06-14 | — | — | US | disclosed |
| US-9365496-B2 | iNKT cell modulators and methods of using the same | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 2016-06-14 | — | — | US | disclosed |
| US-20150010496-A1 | INKT CELL MODULATORS AND METHODS OF USING THE SAME | THE UNIVERSITY OF BIRMINGHAM (GB) | 2015-01-08 | — | — | US | disclosed |
| US-20150010496-A1 | INKT CELL MODULATORS AND METHODS OF USING THE SAME | THE UNIVERSITY OF BIRMINGHAM (GB) | 2015-01-08 | — | — | US | disclosed |
| WO-2013079687-A1 | INKT CELL MODULATORS AND METHODS OF USING THE SAME | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2013-06-06 | — | — | WO | disclosed |
| US-20100174119-A1 | PROCESS FOR THE PREPARATION OF ALDEHYDES | LONZA, LTD. (CH) | 2010-07-08 | — | — | US | disclosed |