Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10336288 | 0.93 | LPAR3 (0.46) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL9638935 | 0.87 | LPAR3 (0.41) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL21051159 | 0.86 | SMPD1 (0.66) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL21051151 | 0.86 | SMPD1 (0.66) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL36372 | 0.86 | SMPD1 (0.66) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL180090 | 0.84 | SMPD1 (0.63) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL6786901 | 0.82 | SMPD1 (0.56) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL19409698 | 0.81 | TSHR (0.54) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL28634001 | 0.81 | LPAR3 (0.46) | SMPD1LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL3975681 | 0.81 | LPAR3 (0.35) | LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071804-A1 | Adhesive for Teeth-Straightening Members | TOKUYAMA DENTAL CORPORATION (JP) | 2013-03-21 | — | — | US | disclosed |
| US-20100184882-A1 | ADHESIVE FOR TEETH-STRAIGHTENING MEMBERS | NIHON UNIVERSITY (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-2149360-A1 | ADHESIVE FOR TEETH-STRAIGHTENING MEMBERS | Nihon University (JP) | 2010-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184882-A1 | ADHESIVE FOR TEETH-STRAIGHTENING MEMBERS | ICAM1, TLN1, COIL | SMPD1 4336/4885LPAR3 2152/4885LPAR2 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.