SCHEMBL29960738

SCHEMBL29960738

CCOC(=O)/C=C/c1sccc1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.49
DPP4 P27487 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
CNKSR1 Q969H4 1/20 0.47
CYP3A4 P08684 2/20 0.47
MAOB P27338 1/20 0.45
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
ESR1 P03372 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
FDPS P14324 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28665758 1.00 TTR (0.49) TTRDPP4CA12CA1CA2
SCHEMBL12660459 0.84 CA12 (0.51) TTRDPP4CA12CA1CA2
SCHEMBL29136968 0.82 TTR (0.49) TTRDPP4CA12CA1CA2
SCHEMBL29302303 0.82 TTR (0.49) TTRDPP4CA12CA1CA2
SCHEMBL29960630 0.81 MAOB (0.57) TTRDPP4CA12CA1CA2
SCHEMBL6755631 0.76 CA12 (0.49) TTRDPP4CA12CA1CA2
SCHEMBL6755628 0.76 CA12 (0.49) TTRDPP4CA12CA1CA2
SCHEMBL9003471 0.75 CA12 (0.51) TTRDPP4CA12CA1CA2
SCHEMBL9003473 0.75 CA12 (0.51) TTRDPP4CA12CA1CA2
SCHEMBL22890669 0.75 KMT2A (0.40) CYP3A4LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed