Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072898 | 1.00 | S1PR4 (0.51) | S1PR4KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL15467609 | 0.92 | S1PR4 (0.50) | S1PR4KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL1631630 | 0.82 | S1PR4 (0.46) | S1PR4KDM4ELMNATRIM24TRIM33 | |
| SCHEMBL29960349 | 0.77 | KDM4E (0.41) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16581566 | 0.77 | KDM4E (0.62) | KDM4ELMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL9051415 | 0.77 | MAPT (0.60) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15432573 | 0.77 | KDM4E (0.48) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9980697 | 0.77 | S1PR4 (0.55) | S1PR4KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL91148 | 0.77 | S1PR4 (0.55) | S1PR4KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL4155091 | 0.77 | S1PR4 (0.55) | S1PR4KDM4ELMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |