SCHEMBL29960913

SCHEMBL29960913

COc1ccc(S(=O)(=O)c2cccc(C)c2)c2[nH]c(=O)n(O)c(=O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FEN1 P39748 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22262113 1.00 FEN1 (1.00) FEN1
SCHEMBL29959978 0.88 FEN1 (1.00) FEN1
SCHEMBL18670556 0.88 FEN1 (1.00) FEN1
SCHEMBL18687691 0.85 FEN1 (1.00) FEN1
SCHEMBL18670439 0.85 FEN1 (1.00) FEN1
SCHEMBL29960045 0.85 FEN1 (1.00) FEN1
SCHEMBL22262184 0.83 FEN1 (0.74) FEN1
SCHEMBL22262281 0.83 FEN1 (0.74) FEN1
SCHEMBL29960108 0.83 FEN1 (0.74) FEN1
SCHEMBL29959973 0.83 FEN1 (0.74) FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430978-B 3-hydroxy-quinazoline-2, 4-dione derivatives and their use as nuclease modulators 路德维格癌症研究所有限责任公司 2022-11-22 — — CN disclosed
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