Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 13/20 | 0.70 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.70 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.70 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.70 |
| ▸ | P4HTM | Q9NXG6 | 7/20 | 0.65 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963867 | 0.91 | EGLN2 (0.66) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL564894 | 0.91 | EGLN2 (0.74) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL29963973 | 0.90 | EGLN2 (0.67) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL29964077 | 0.89 | EGLN2 (0.69) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL29963993 | 0.88 | EGLN2 (0.76) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL563832 | 0.87 | EGLN2 (0.68) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL4752398 | 0.87 | EGLN2 (0.76) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL29964305 | 0.86 | EGLN2 (0.73) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL4752395 | 0.85 | EGLN2 (0.82) | EGLN2EGLN1HIF1ANEGLN3P4HTM | |
| SCHEMBL564938 | 0.85 | EGLN2 (0.70) | EGLN2EGLN1HIF1ANEGLN3P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694380-B | Dihydropyrazolone compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-109694380-B | Dihydropyrazolone compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-09-27 | — | — | CN | disclosed |