Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | DHODH | Q02127 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621768 | 1.00 | MAPT (0.54) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 | |
| SCHEMBL20600156 | 0.83 | RXFP1 (0.41) | MAPTGAADHODHKDM4EMEN1 | |
| SCHEMBL10862709 | 0.83 | CYP3A4 (0.67) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 | |
| SCHEMBL20621792 | 0.81 | CYP3A4 (0.50) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 | |
| SCHEMBL29965238 | 0.81 | CYP3A4 (0.50) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 | |
| SCHEMBL20621881 | 0.81 | CYP3A4 (0.50) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 | |
| SCHEMBL29965230 | 0.81 | MAPT (0.56) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 | |
| SCHEMBL20622111 | 0.81 | CYP3A4 (0.52) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 | |
| SCHEMBL20621799 | 0.81 | MAPT (0.56) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 | |
| SCHEMBL10859795 | 0.81 | MAPT (0.64) | MAPTCYP3A4CYP2D6CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615527-B1 | NEW AZAQUINOLINE DERIVATIVES | ELANCO ANIMAL HEALTH GMBH (DE) | 2024-03-06 | — | — | EP | disclosed |
| US-11485733-B2 | Azaquinoline derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2022-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485733-B2 | Azaquinoline derivatives | RECQL, H1-5, H1-3 | MAPT 4349/4885CYP3A4 314/4885CYP2D6 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.