SCHEMBL29965281

SCHEMBL29965281

Nc1ncccc1C(=O)Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 3/20 1.00
MEN1 O00255 6/20 0.65
KMT2A Q03164 6/20 0.65
ALDH1A1 P00352 3/20 0.65
MAPT P10636 3/20 0.65
GAA P10253 1/20 0.65
ATR Q13535 1/20 0.64
NAPRT Q6XQN6 1/20 0.61
VCP P55072 2/20 0.55
EGLN1 Q9GZT9 1/20 0.55
KDM4E B2RXH2 2/20 0.55
LMNA P02545 2/20 0.55
HTT P42858 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
GLA P06280 1/20 0.55
HPGD P15428 2/20 0.54
TP53 P04637 1/20 0.54
HSD17B10 Q99714 1/20 0.54
MAPK1 P28482 1/20 0.52
RAB9A P51151 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25565213 1.00 PRKCI (1.00) PRKCIMEN1KMT2AALDH1A1MAPT
SCHEMBL1944860 0.86 PRKCI (0.75) PRKCIMEN1KMT2AALDH1A1MAPT
SCHEMBL12857647 0.86 PRKCI (0.75) PRKCIMEN1KMT2AALDH1A1MAPT
SCHEMBL25437975 0.86 PRKCI (0.75) PRKCIMEN1KMT2AALDH1A1MAPT
SCHEMBL30442378 0.86 PRKCI (0.75) PRKCIMEN1KMT2AALDH1A1MAPT
SCHEMBL259303 0.82 PRKCI (0.69) PRKCIMEN1KMT2AALDH1A1VCP
SCHEMBL8179072 0.82 PRKCI (0.68) PRKCIMEN1KMT2AALDH1A1MAPT
SCHEMBL16512863 0.81 MEN1 (0.75) PRKCIMEN1KMT2AALDH1A1MAPT
SCHEMBL9379517 0.81 PRKCI (0.68) PRKCIMEN1KMT2AALDH1A1MAPT
SCHEMBL13175094 0.80 PRKCI (0.67) PRKCIMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4433469-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI Industries Ltd. (IN) 2024-09-25 EP disclosed
WO-2023084473-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2023-05-19 WO disclosed
EP-3873468-A4 2-AMINO-N-PHENYL-NICOTINAMIDES AS NAV1.8 INHIBITORS Merck Sharp & Dohme LLC (US) 2022-10-26 EP disclosed