Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 8/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811811 | 0.84 | NR1H2 (0.40) | NR1H2OXER1HSP90AA1HSP90AB1NR1H3 | |
| SCHEMBL1760804 | 0.84 | NR1H2 (0.40) | NR1H2OXER1HSP90AA1HSP90AB1NR1H3 | |
| SCHEMBL29964999 | 0.83 | NR1H2 (0.37) | NR1H2OXER1HSP90AA1HSP90AB1NR1H3 | |
| SCHEMBL18992998 | 0.83 | HSP90AA1 (0.41) | NR1H2OXER1HSP90AA1HSP90AB1NR1H3 | |
| SCHEMBL31370781 | 0.83 | NR1H2 (0.49) | NR1H2OXER1HSP90AA1HSP90AB1NR1H3 | |
| SCHEMBL1053719 | 0.82 | NR1H2 (0.43) | NR1H2OXER1HSP90AA1HSP90AB1NR1H3 | |
| SCHEMBL31370682 | 0.81 | NR1H2 (0.42) | NR1H2OXER1HSP90AA1HSP90AB1NR1H3 | |
| SCHEMBL29919526 | 0.80 | OXER1 (0.41) | MAOBMAOAOXER1KDM4EALDH1A1 | |
| SCHEMBL30933401 | 0.78 | HSP90AA1 (0.35) | NR1H2MAOBHSP90AA1HSP90AB1NR1H3 | |
| SCHEMBL15231776 | 0.78 | NR1H2 (0.35) | NR1H2OXER1NR1H3PIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151540-A | Polyheterocyclic compounds as METTL3 inhibitors | 风暴治疗有限公司 | 2022-10-04 | — | — | CN | disclosed |