Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 8/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 4/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21262531 | 1.00 | TNIK (0.60) | TNIKDYRK1ACDK5CDK2CDK1 | |
| SCHEMBL21262456 | 0.86 | TNIK (0.63) | TNIKDYRK1ACDK2CDK1NPC1 | |
| SCHEMBL21262535 | 0.85 | TNIK (0.65) | TNIKDYRK1ACDK2CDK1NPY5R | |
| SCHEMBL30224996 | 0.85 | TNIK (0.65) | TNIKDYRK1ACDK2CDK1NPY5R | |
| SCHEMBL21262761 | 0.83 | TNIK (0.57) | TNIKDYRK1ACDK2CDK1NPC1 | |
| SCHEMBL29966402 | 0.83 | TNIK (0.57) | TNIKDYRK1ACDK2CDK1NPC1 | |
| SCHEMBL29966127 | 0.81 | CSNK2A2 (0.64) | TNIKCDK2CDK1NPC1RAB9A | |
| SCHEMBL21262534 | 0.81 | TNIK (0.70) | TNIKNPC1RAB9ANPY5RCSNK2A2 | |
| SCHEMBL21262532 | 0.81 | CSNK2A2 (0.64) | TNIKCDK2CDK1NPC1RAB9A | |
| SCHEMBL29965727 | 0.81 | TNIK (0.70) | TNIKNPC1RAB9ANPY5RCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767297-B2 | Compounds for inhibiting TNIK and medical uses thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2023-09-26 | — | — | US | disclosed |
| US-20230039679-A1 | COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2023-02-09 | — | — | US | disclosed |
| US-11485711-B2 | Compounds for inhibiting TNIK and medical uses thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2022-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767297-B2 | Compounds for inhibiting TNIK and medical uses thereof | TNNI3K, TNK1, TNIK | TNIK 3/4885DYRK1A 1035/4885CDK5 1073/4885 |
| US-11485711-B2 | Compounds for inhibiting TNIK and medical uses thereof | TNNI3K, TNK1, TNIK | TNIK 3/4885DYRK1A 1035/4885CDK5 1073/4885 |
| US-20230039679-A1 | COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF | TNNI3K, TNK1, TNIK | TNIK 3/4885DYRK1A 1035/4885CDK5 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.