Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.74 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.64 |
| ▸ | PIM1 | P11309 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.64 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.56 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.52 |
| ▸ | TEK | Q02763 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24819 | 1.00 | PARP1 (0.74) | PARP1CHEK1PIM1ALDH1A1RPS6KA3 | |
| SCHEMBL6922381 | 0.88 | PARP1 (0.63) | PARP1CHEK1PIM1ALDH1A1RPS6KA3 | |
| SCHEMBL29709603 | 0.85 | PARP1 (1.00) | PARP1CHEK1PIM1ALDH1A1IP6K1 | |
| SCHEMBL2191067 | 0.85 | PARP1 (1.00) | PARP1CHEK1PIM1ALDH1A1IP6K1 | |
| Hydrochloric Acid SCHEMBL30141968 | 0.84 | PARP1 (0.96) | PARP1CHEK1PIM1IP6K1IP6K3 | |
| SCHEMBL6921163 | 0.82 | TEK (0.59) | PARP1CHEK1PIM1ALDH1A1RPS6KA3 | |
| SCHEMBL2051742 | 0.82 | IP6K1 (0.59) | PARP1CHEK1PIM1ALDH1A1RPS6KA3 | |
| SCHEMBL2047492 | 0.79 | IP6K1 (0.59) | PARP1CHEK1PIM1ALDH1A1RPS6KA3 | |
| SCHEMBL5875318 | 0.78 | IP6K1 (0.61) | PARP1CHEK1PIM1ALDH1A1RPS6KA3 | |
| SCHEMBL391295 | 0.78 | PIM1 (0.74) | PARP1CHEK1PIM1ALDH1A1RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118996447-A | Phosphine-oxide substituted quinoxaline quinazolinone compound, preparation method and application thereof | 南阳师范学院 | 2024-11-22 | — | — | CN | claimed |
| CN-115252554-B | Preparation, composition and application of novel 4 (3H) -quinazolinone analogue/cyclic dinucleotide cGAMP co-carrier liposome in antitumor drugs | 杭州星鳌生物科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-115702939-A | Multi-target complex of cargo liposome, drug-loading platform containing multi-target complex and application of multi-target complex | 杭州星鳌生物科技有限公司 | 2023-02-17 | — | — | CN | claimed |
| WO-2023011076-A1 | MULTI-TARGET COMPLEX OF LOADED LIPOSOME AND DRUG-LOADED PLATFORM CONTAINING SAME AND APPLICATION | 杭州星鳌生物科技有限公司 | 2023-02-09 | — | — | WO | claimed |
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| CN-119950718-A | Pharmaceutical composition containing STING agonist and application thereof | 杭州星鳌生物科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |
| CN-111699176-B | Quinazolinones as PARP14 inhibitors | 里邦医疗公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114025755-B | Therapeutic use of heterocyclic compounds as kinase inhibitors | 台湾卫生研究院 | 2024-11-29 | — | — | CN | disclosed |
| CN-118996447-A | Phosphine-oxide substituted quinoxaline quinazolinone compound, preparation method and application thereof | 南阳师范学院 | 2024-11-22 | — | — | CN | disclosed |
| CN-115252554-B | Preparation, composition and application of novel 4 (3H) -quinazolinone analogue/cyclic dinucleotide cGAMP co-carrier liposome in antitumor drugs | 杭州星鳌生物科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-116120326-A | Alpha-methyl deoxidized duckbill alkali ketone compound and synthesis method thereof | 常州大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-113637011-B | Myricetin derivative containing quinazoline-4 (3H) -ketone and preparation method and application thereof | 贵州大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-115702939-A | Multi-target complex of cargo liposome, drug-loading platform containing multi-target complex and application of multi-target complex | 杭州星鳌生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| WO-2023011076-A1 | MULTI-TARGET COMPLEX OF LOADED LIPOSOME AND DRUG-LOADED PLATFORM CONTAINING SAME AND APPLICATION | 杭州星鳌生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| WO-2022233253-A1 | METHOD FOR PREPARING NEW 4(3H)-QUINAZOLINONE ANALOG, STRUCTURAL COMPOSITION THEREOF, AND USE THEREOF IN ANTITUMOR DRUGS | 杭州星鳌生物科技有限公司 | 2022-11-10 | — | — | WO | disclosed |
| CN-115252554-A | Preparation and composition of novel 4 (3H) -quinazolinone analogue/cyclic dinucleotide cGAMP (cyclic-gated AMP) co-carried liposome and application of liposome in antitumor drugs | 杭州星鳌生物科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115260164-A | Preparation method and structural composition of novel 4 (3H) -quinazolinone analogue and application of analogue in antitumor drugs | 杭州星鳌生物科技有限公司 | 2022-11-01 | — | — | CN | disclosed |