Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL27491710 | 1.00 | HCAR2 (0.37) | HCAR2KEAP1NFE2L2NPSR1ALDH1A1 | |
| Acrylic Acid Methyl Ester SCHEMBL27994341 | 0.98 | HCAR2 (0.39) | HCAR2KEAP1NFE2L2NPSR1ALDH1A1 | |
| Acrylic Acid Methyl Ester SCHEMBL27729557 | 0.87 | — | — | |
| Acrylic Acid Methyl Ester SCHEMBL29212937 | 0.87 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| Cyclohexane SCHEMBL16179835 | 0.87 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| Acrylic Acid Methyl Ester SCHEMBL8408215 | 0.87 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| Acrylic Acid Methyl Ester SCHEMBL6915690 | 0.87 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| Acrylic Acid Methyl Ester SCHEMBL27944026 | 0.86 | EPHX1 (0.41) | HCAR2KEAP1NFE2L2NPSR1ALDH1A1 | |
| Cyclohexanol SCHEMBL27472224 | 0.86 | TSHR (0.40) | HCAR2KEAP1NFE2L2NPSR1ALDH1A1 | |
| Acrylic Acid Methyl Ester SCHEMBL29280950 | 0.84 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |