Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30111895 | 1.00 | TLR7 (0.39) | TLR7KCNH2APPACHEPDE1A | |
| SCHEMBL23703886 | 0.95 | TLR7 (0.39) | TLR7KCNH2APPACHEPDE1A | |
| SCHEMBL29970727 | 0.95 | TLR7 (0.40) | TLR7KCNH2APPACHE | |
| SCHEMBL30111898 | 0.95 | TLR7 (0.40) | TLR7KCNH2APPACHE | |
| SCHEMBL23704543 | 0.89 | TLR7 (0.40) | TLR7KCNH2APPACHE | |
| SCHEMBL29971178 | 0.89 | TLR7 (0.42) | TLR7KCNH2 | |
| SCHEMBL23718892 | 0.88 | TLR7 (0.55) | TLR7KCNH2 | |
| SCHEMBL23718889 | 0.84 | TLR7 (0.42) | TLR7KCNH2 | |
| SCHEMBL29971148 | 0.84 | TLR7 (0.42) | TLR7KCNH2 | |
| SCHEMBL23704586 | 0.83 | TLR7 (0.43) | TLR7KCNH2APPACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135654-A | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7(TLR7) agonists | 百时美施贵宝公司 | 2022-09-30 | — | — | CN | disclosed |