Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 18/20 | 1.00 |
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17273966 | 0.84 | KDM4E (0.79) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL20324858 | 0.82 | KDM4E (0.71) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL5508014 | 0.82 | KDM4E (0.76) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL298858 | 0.79 | KDM4E (1.00) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL20325233 | 0.78 | KDM4E (0.69) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL20322400 | 0.76 | KDM4E (0.66) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL18494882 | 0.75 | KDM4E (0.61) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL3076290 | 0.74 | KDM4E (0.58) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL3035445 | 0.73 | KDM4E (0.71) | KDM4ERAB9ANPC1PKMLMNA | |
| SCHEMBL17229235 | 0.72 | KDM4E (0.58) | KDM4ERAB9ANPC1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | claimed |
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |