SCHEMBL29972957

CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)[C@@H](C)CC

nearest known ligand 0.62

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	19/20	0.62

▸	BACE1	P56817	1/20	0.56

▸	BACE2	Q9Y5Z0	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29973096	0.97	GLP1R (0.60)	GLP1RBACE1BACE2
Sovatelitide SCHEMBL29405690	0.94	GLP1R (0.61)	GLP1R
SCHEMBL30423068	0.92	GLP1R (0.59)	GLP1R
SCHEMBL29973282	0.90	EDNRA (0.56)	GLP1R
SCHEMBL30524411	0.89	GLP1R (0.59)	GLP1R
SCHEMBL29973297	0.88	GLP1R (0.62)	GLP1R
SCHEMBL29973649	0.88	GLP1R (0.61)	GLP1R
SCHEMBL31182770	0.88	GLP1R (0.73)	GLP1R
SCHEMBL30605039	0.88	GLP1R (0.69)	GLP1R
SCHEMBL29418257	0.87	BACE1 (0.62)	GLP1RBACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4067370-A1	HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS	Yu, Chongxi (US)	2022-10-05	—	—	EP	disclosed