⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6350 | 0.97 | — | — | |
| SCHEMBL6205331 | 0.97 | — | — | |
| SCHEMBL29520025 | 0.97 | — | — | |
| SCHEMBL28445086 | 0.94 | — | — | |
| SCHEMBL31300427 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL2815704 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL509987 | 0.94 | — | — | |
| Bromide SCHEMBL2221070 | 0.94 | — | — | |
| SCHEMBL22462301 | 0.94 | — | — | |
| SCHEMBL31574212 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947897-B | Novel preparation method of nicorandam | 浙江金伯士药业有限公司 | 2020-04-24 | — | — | CN | claimed |
| CN-104558091-A | Synthesis method of abiraterone acetate | TIANJIN JINYAO GROUP CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-102898495-B | Method for preparing abiraterone acetate | ZHEJIANG SHENZHOU PHARMACEUTICAL CO LTD | 2014-11-26 | — | — | CN | claimed |
| CN-102898495-A | Method for preparing abiraterone acetate | ZHEJIANG SHENZHOU PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | claimed |
| US-20250296952-A1 | METHOD FOR PREPARING ABIRATERONE ACETATE AND INTERMEDIATE THEREOF | AURISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-09-25 | — | — | US | disclosed |
| CN-108947897-B | Novel preparation method of nicorandam | 浙江金伯士药业有限公司 | 2020-04-24 | — | — | CN | disclosed |
| CN-105324379-A | Benzimidazole derivatives as bromodomain inhibitors | GILEAD SCIENCES INC | 2016-02-10 | — | — | CN | disclosed |
| CN-104558091-A | Synthesis method of abiraterone acetate | TIANJIN JINYAO GROUP CO LTD | 2015-04-29 | — | — | CN | disclosed |
| EP-2841444-A1 | PROCESS FOR PREPARATION OF 17-SUBSTITUTED STEROIDS | Alphora Research Inc. (CA) | 2015-03-04 | — | — | EP | disclosed |
| CN-102898495-B | Method for preparing abiraterone acetate | ZHEJIANG SHENZHOU PHARMACEUTICAL CO LTD | 2014-11-26 | — | — | CN | disclosed |
| WO-2013159225-A1 | PROCESS FOR PREPARATION OF 17-SUBSTITUTED STEROIDS | ALPHORA RESEARCH INC. (CA) | 2013-10-31 | — | — | WO | disclosed |
| CN-102898495-A | Method for preparing abiraterone acetate | ZHEJIANG SHENZHOU PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | disclosed |
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
| US-6180629-B1 | INDUCING OR PROMOTING APOPTOSIS AND FOR ARRESTING UNCONTROLLED NEOPLASTIC CELL PROLIFERATION, INCLUDING PRECANCEROUS AND CANCEROUS LESIONS | CELL PATHWAYS, INC. | 2001-01-30 | — | — | US | disclosed |
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1990000170-A1 | NOVEL 6-AMIDO-1-METHYLCARBAPENEMS | MERCK & CO., INC. (US) | 1990-01-11 | — | — | WO | disclosed |
| EP-0350211-A2 | Novel 6-amido-1-methyl carbapenems | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4499287-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4316905-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |
| US-4291040-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1981-09-22 | — | — | US | disclosed |