Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579383 | 1.00 | BCL2 (0.41) | BCL2BCL2L1PTGS1PTGS2CYP11B1 | |
| SCHEMBL29972748 | 0.89 | MAPT (0.38) | — | |
| SCHEMBL23579424 | 0.89 | MAPT (0.38) | — | |
| SCHEMBL22658124 | 0.79 | PDE4B (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL28106581 | 0.79 | CYP3A4 (0.48) | BCL2BCL2L1PTGS1PTGS2CYP11B1 | |
| SCHEMBL24254882 | 0.78 | HSD17B10 (0.50) | ALOX5PTGDR2ALDH1A1HSD17B10 | |
| SCHEMBL10703351 | 0.77 | HTR2A (0.48) | BCL2BCL2L1CYP11B1CYP11B2HTR2A | |
| SCHEMBL10713368 | 0.76 | PTGS1 (0.50) | PTGS1PTGS2PTGDR2ALDH1A1 | |
| SCHEMBL31457309 | 0.75 | CYP3A4 (0.45) | PTGS1PTGS2CYP11B1CYP11B2PTGDR2 | |
| SCHEMBL27485032 | 0.74 | CYP11B1 (0.45) | CYP11B1CYP11B2HTR2ACALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |