Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.65 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696978 | 0.94 | GNPAT (0.63) | GNPATSIRT6SIRT1KDM4EMAPT | |
| SCHEMBL31615759 | 0.90 | GNPAT (0.59) | GNPATSIRT6SIRT1KDM4EMAPT | |
| SCHEMBL31615037 | 0.90 | GNPAT (0.59) | GNPATSIRT6SIRT1KDM4EMAPT | |
| SCHEMBL31615880 | 0.90 | GNPAT (0.59) | GNPATSIRT6SIRT1KDM4EMAPT | |
| SCHEMBL12729522 | 0.86 | GNPAT (0.63) | GNPATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30152075 | 0.86 | GNPAT (0.59) | GNPATSIRT6SIRT1SIRT5MME | |
| SCHEMBL29833617 | 0.86 | GNPAT (0.51) | GNPATENPEPMMENOD1EPHX2 | |
| SCHEMBL22862417 | 0.85 | GNPAT (0.69) | GNPATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL31688028 | 0.83 | GNPAT (0.52) | GNPATSIRT6SIRT1KDM4EMAPT | |
| SCHEMBL137690 | 0.83 | SMN1; SMN2 (0.55) | GNPATSIRT6SIRT1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143881-A | Preparation method of bumenopeptide | 深圳市健元医药科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-113621022-B | Synthesis method of cyclic peptide | 甘肃瑞德林生物有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117843715-A | Liquid phase synthesis method of melanoputan-II | 浙江工业大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-116640182-A | Transdermal delivery system for polypeptides and related compounds | 泰飞尔生物医药(苏州)有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-116143881-A | Preparation method of bumenopeptide | 深圳市健元医药科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116143881-A | Preparation method of bumenopeptide | 深圳市健元医药科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4067370-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS | Yu, Chongxi (US) | 2022-10-05 | — | — | EP | disclosed |