Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 10/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.44 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | GIPR | P48546 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389069 | 1.00 | BACE1 (0.51) | BACE1BACE2CTSDGRIN2DGRIN3B | |
| SCHEMBL29386588 | 1.00 | BACE1 (0.51) | BACE1BACE2CTSDGRIN2DGRIN3B | |
| SCHEMBL29711237 | 0.98 | BACE1 (0.49) | BACE1BACE2CTSDGRIN2DGRIN3B | |
| SCHEMBL30512635 | 0.93 | BACE1 (0.46) | BACE1BACE2CTSDGRIN2DGRIN3B | |
| SCHEMBL30578948 | 0.90 | BACE1 (0.43) | BACE1BACE2CTSD | |
| SCHEMBL30842794 | 0.89 | BACE1 (0.46) | BACE1CTSD | |
| SCHEMBL30242246 | 0.88 | FOLH1 (0.43) | BACE1BACE2CTSDGRIN2DGRIN3B | |
| SCHEMBL31341151 | 0.88 | BACE1 (0.56) | BACE1BACE2CTSD | |
| SCHEMBL30974509 | 0.88 | GRIN2D (0.56) | BACE1BACE2CTSDGRIN2DGRIN3B | |
| SCHEMBL30512779 | 0.87 | BACE1 (0.52) | BACE1BACE2CTSDGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4067370-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS | Yu, Chongxi (US) | 2022-10-05 | — | — | EP | disclosed |