SCHEMBL29973739

CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)[C@@H](C)O)C(C)C)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	18/20	0.51

▸	SCTR	P47872	1/20	0.51

▸	TFPI	P10646	1/20	0.45

▸	KEAP1	Q14145	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30462284	0.89	GLP1R (0.55)	GLP1RSCTRTFPI
SCHEMBL31307238	0.88	GLP1R (0.61)	GLP1RSCTR
SCHEMBL30613906	0.87	VIPR2 (0.49)	GLP1RKEAP1
SCHEMBL30648447	0.86	GLP1R (0.59)	GLP1RSCTR
SCHEMBL30277571	0.86	TFPI (0.58)	GLP1RSCTRTFPI
SCHEMBL31410848	0.85	GLP1R (0.62)	GLP1RSCTRKEAP1
SCHEMBL30512578	0.85	GLP1R (0.48)	GLP1RSCTR
SCHEMBL30524371	0.85	GLP1R (0.56)	GLP1RSCTRKEAP1
SCHEMBL31410870	0.85	GLP1R (0.61)	GLP1RSCTRKEAP1
SCHEMBL31419696	0.84	GLP1R (0.51)	GLP1RSCTRKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4067370-A1	HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS	Yu, Chongxi (US)	2022-10-05	—	—	EP	disclosed