Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 13/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650190 | 1.00 | ESR2 (0.54) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL29407529 | 0.89 | ESR2 (0.70) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL29407557 | 0.89 | NR1H2 (0.69) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL1285596 | 0.89 | NR1H2 (0.69) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL168265 | 0.89 | ESR2 (0.70) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL4050983 | 0.89 | ESR2 (0.52) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL18379840 | 0.87 | ESR2 (0.53) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL8921662 | 0.87 | NR1H2 (0.55) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL30895660 | 0.87 | ESR2 (0.53) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL18883051 | 0.87 | ESR2 (0.53) | ESR2HDAC1NR1H2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397811-B | Isoindoline derivatives binding to ATP binding sites | 奈奥芬莱有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-118317954-A | Indoline as PROTAC compound | 奈奥芬莱有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115397811-A | Isoindoline derivatives that bind to ATP binding sites | 奈奥芬莱有限公司 | 2022-11-25 | — | — | CN | disclosed |