Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bilobalide SCHEMBL14029382 | 0.84 | KMT2A (1.00) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| Bilobalide SCHEMBL29410789 | 0.84 | KMT2A (1.00) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| Bilobalide SCHEMBL19236272 | 0.84 | KMT2A (1.00) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| Bilobalide SCHEMBL13960090 | 0.84 | KMT2A (1.00) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| Bilobalide SCHEMBL29410808 | 0.84 | KMT2A (1.00) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| Bilobalide SCHEMBL16653675 | 0.84 | KMT2A (1.00) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| Bilobalide SCHEMBL18327718 | 0.84 | KMT2A (1.00) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| Bilobalide SCHEMBL16452769 | 0.84 | KMT2A (1.00) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| SCHEMBL19274834 | 0.73 | MEN1 (0.62) | MEN1THRBALOX15KMT2ASMN1; SMN2 | |
| SCHEMBL31364706 | 0.70 | MEN1 (0.65) | MEN1THRBALOX15KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141169-B | Terpene lactone derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-115141169-A | Terpene lactone derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2022-10-04 | — | — | CN | disclosed |