Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.47 |
| ▸ | INSR | P06213 | 3/20 | 0.47 |
| ▸ | IGF1R | P08069 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084155 | 0.90 | EGFR (0.56) | EGFRPLK1ALKINSRIGF1R | |
| SCHEMBL29084090 | 0.89 | EGFR (0.55) | EGFRPLK1FGFR3ALKINSR | |
| SCHEMBL29084000 | 0.89 | EGFR (0.56) | EGFRPLK1FGFR3ALKINSR | |
| SCHEMBL29084051 | 0.89 | EGFR (0.56) | EGFRPLK1ALKINSRIGF1R | |
| SCHEMBL29084038 | 0.89 | EGFR (0.54) | EGFRPLK1FGFR3ALKINSR | |
| SCHEMBL29083992 | 0.88 | EGFR (0.54) | EGFRPLK1ALKINSRIGF1R | |
| SCHEMBL29084066 | 0.88 | EGFR (0.55) | EGFRPLK1FGFR3ALKINSR | |
| SCHEMBL29083959 | 0.87 | EGFR (0.53) | EGFRPLK1ALKINSRIGF1R | |
| SCHEMBL29084086 | 0.86 | EGFR (0.53) | EGFRPLK1ALKINSRIGF1R | |
| SCHEMBL29084091 | 0.85 | EGFR (0.53) | EGFRPLK1ALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | disclosed |