Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 1.00 |
| ▸ | IGF1R | P08069 | 4/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 4/20 | 1.00 |
| ▸ | INSR | P06213 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14719159 | 1.00 | EGFR (1.00) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL14719220 | 1.00 | EGFR (1.00) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL17373106 | 1.00 | EGFR (1.00) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL19493247 | 0.96 | EGFR (0.92) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL16668610 | 0.95 | EGFR (1.00) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28942022 | 0.94 | EGFR (0.88) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28942107 | 0.94 | EGFR (0.88) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28464059 | 0.94 | EGFR (0.88) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28460779 | 0.94 | EGFR (0.88) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL14718869 | 0.91 | EGFR (0.84) | EGFRIGF1RKCNH2INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4086246-A1 | 2-(2,4,5-SUBSTITUTED-ANILINO)PYRIMIDINE COMPOUNDS AS EGFR MODULATORS | AstraZeneca AB (SE) | 2022-11-09 | — | — | EP | disclosed |