SCHEMBL29975529

SCHEMBL29975529

CC(C)(C)OC(=O)N[C@H]1CCN(C(=O)c2ccc(Cl)c(-c3ccc(C#N)c(F)c3)c2)C1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 17/20 0.53
GPR119 Q8TDV5 1/20 0.49
BRD4 O60885 1/20 0.48
KDM4D Q6B0I6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20512887 1.00 KDM1A (0.53) KDM1AGPR119BRD4KDM4D
SCHEMBL20512767 0.89 KDM1A (0.70) KDM1A
SCHEMBL20512896 0.88 KDM1A (0.57) KDM1AKDM4D
SCHEMBL20512594 0.87 KDM1A (0.59) KDM1A
SCHEMBL20512904 0.86 KDM1A (0.55) KDM1A
SCHEMBL20512563 0.86 KDM1A (0.55) KDM1A
SCHEMBL20512562 0.86 KDM1A (0.55) KDM1A
SCHEMBL23496011 0.85 KDM1A (0.48) KDM1AGPR119KDM4D
SCHEMBL20512481 0.85 KDM1A (0.48) KDM1AGPR119KDM4D
SCHEMBL20512595 0.84 KDM1A (0.75) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11510915-B2 Anti-tumor effect potentiator using novel biphenyl compound TAIHO PHARMACEUTICAL CO., LTD. (JP) 2022-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11510915-B2 Anti-tumor effect potentiator using novel biphenyl compound KDM1B, KDM1A, DOT1L KDM1A 2/4885GPR119 577/4885BRD4 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.