⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26880637 | 1.00 | — | — | |
| SCHEMBL26093344 | 1.00 | — | — | |
| SCHEMBL26093349 | 1.00 | — | — | |
| SCHEMBL30390775 | 1.00 | — | — | |
| SCHEMBL31026727 | 1.00 | — | — | |
| SCHEMBL26888015 | 1.00 | — | — | |
| SCHEMBL26093347 | 1.00 | — | — | |
| SCHEMBL30296568 | 0.89 | — | — | |
| SCHEMBL30296397 | 0.89 | — | — | |
| SCHEMBL30296341 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2025124456-A1 | ANTIBODY DRUG CONJUGATE PLATFORMS | BEIGENE, LTD. (KY) | 2025-06-19 | — | — | WO | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |
| EP-4330258-A1 | COMPOUNDS | Pathios Therapeutics Limited (GB) | 2024-03-06 | — | — | EP | disclosed |
| US-20240051961-A1 | N-(PYRIDIN-2-YL)-6,7,8,9-TETRAHYDRO-5H-5,8-EPIMINOCYCLOHEPTA[C]PYRIDINE-10-CARBOXAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS GPR65 MODULATORS FOR THE TREATMENT OF CANCER | Pathios Therapeutics Limited (GB) | 2024-02-15 | — | — | US | disclosed |
| CN-116783195-A | N-phenylaminocarbonyl pyridinyl-, pyrimidinyl and benzo-tropanes as modulators of GPR65 | 帕蒂奥斯治疗有限公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-4161642-A1 | N-PHENYLAMINOCARBONYL PYRIDINO-, PYRIMIDINO AND BENZO-TROPANES AS MODULATORS OF GPR65 | Pathios Therapeutics Limited (GB) | 2023-04-12 | — | — | EP | disclosed |
| WO-2022229615-A1 | COMPOUNDS | Pathios Therapeutics Limited (GB) | 2022-11-03 | — | — | WO | disclosed |