SCHEMBL29975937

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29364610	1.00	MAPT (0.61)	MAPTABCB1HSD17B10GRIN2DGRIN3B
	SCHEMBL20090288	1.00	MAPT (0.61)	MAPTABCB1HSD17B10GRIN2DGRIN3B
	SCHEMBL315297	0.80	MAPT (0.53)	MAPTABCB1HSD17B10GRIN2DGRIN3B
	SCHEMBL20348696	0.79	ABCB1 (0.75)	MAPTABCB1HSD17B10PARP1KMT2A
	SCHEMBL24237163	0.78	MAPT (0.42)	MAPTABCB1HSD17B10GRIN2DGRIN3B
	SCHEMBL14292167	0.77	PDK2 (0.50)	MAPTABCB1HSD17B10GRIN2DGRIN3B
	SCHEMBL315296	0.77	MAPT (0.50)	MAPTABCB1HSD17B10GRIN2DGRIN3B
	SCHEMBL29617331	0.77	MAPT (0.60)	MAPTABCB1HSD17B10GRIN2DGRIN3B
	SCHEMBL19689950	0.77	MAPT (0.60)	MAPTABCB1HSD17B10GRIN2DGRIN3B
	SCHEMBL8807640	0.75	HSD17B10 (0.52)	MAPTABCB1HSD17B10GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.