SCHEMBL29975965

SCHEMBL29975965

CCOC(=O)CCC(=O)c1cc2cc(O)c(OC)cc2s1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 17/20 0.76
ACHE P22303 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24450978 1.00 STING1 (0.76) STING1ACHE
SCHEMBL20022332 0.95 STING1 (0.76) STING1ACHE
SCHEMBL20022337 0.91 STING1 (0.81) STING1ACHE
SCHEMBL30820009 0.91 STING1 (0.81) STING1ACHE
SCHEMBL30416359 0.88 STING1 (0.65) STING1ACHE
SCHEMBL21406087 0.88 STING1 (0.65) STING1ACHE
SCHEMBL21436944 0.88 STING1 (0.60) STING1ACHE
SCHEMBL25693866 0.88 STING1 (0.64) STING1ACHE
SCHEMBL29976155 0.88 STING1 (0.64) STING1ACHE
SCHEMBL21452559 0.87 STING1 (0.63) STING1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024175086-A1 ARYL TRICYCLIC STING AGONIST AND USE THEREOF 深圳真实生物医药科技有限公司 2024-08-29 WO disclosed
CN-113518776-B Benzothiophene compound and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2024-03-26 CN disclosed
WO-2024032782-A1 VACCINE ADJUVANTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO.LTD. (CN) 2024-02-15 WO disclosed
EP-4313962-A1 NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF Jacobio Pharmaceuticals Co., Ltd. (CN) 2024-02-07 EP disclosed
CN-117203194-A Novel compounds useful as STING agonists and uses thereof 北京加科思新药研发有限公司 2023-12-08 CN disclosed
WO-2023109942-A1 COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 WO disclosed
WO-2022206725-A1 NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-10-06 WO disclosed