SCHEMBL29976247

SCHEMBL29976247

CCOC(=O)CCC(=O)c1cc2cc(Br)c(OCOC)cc2s1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 19/20 0.79
PTPN2 P17706 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25693725 1.00 STING1 (0.79) STING1PTPN2
SCHEMBL21452623 0.89 STING1 (0.61) STING1
SCHEMBL20022266 0.89 STING1 (1.00) STING1
SCHEMBL25693866 0.88 STING1 (0.64) STING1
SCHEMBL29976155 0.88 STING1 (0.64) STING1
SCHEMBL21452768 0.84 STING1 (0.61) STING1
SCHEMBL20022243 0.84 STING1 (1.00) STING1
SCHEMBL25280963 0.81 STING1 (0.74) STING1PTPN2
SCHEMBL30666369 0.81 STING1 (0.74) STING1PTPN2
SCHEMBL20022337 0.81 STING1 (0.81) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024032782-A1 VACCINE ADJUVANTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO.LTD. (CN) 2024-02-15 WO disclosed
EP-4313962-A1 NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF Jacobio Pharmaceuticals Co., Ltd. (CN) 2024-02-07 EP disclosed
WO-2023109942-A1 COMPOUND-LINKER CONSTRUCTS COMPRISING NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 WO disclosed
WO-2022206725-A1 NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-10-06 WO disclosed