Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629620 | 1.00 | TACR1 (0.72) | TACR1 | |
| SCHEMBL30307065 | 1.00 | TACR1 (0.72) | TACR1 | |
| Hydrochloric Acid SCHEMBL7823238 | 0.99 | TACR1 (0.71) | TACR1 | |
| Water SCHEMBL7834521 | 0.99 | TACR1 (0.71) | TACR1 | |
| Hydrochloric Acid SCHEMBL7833330 | 0.99 | TACR1 (0.70) | TACR1 | |
| Oxalic Acid SCHEMBL8748967 | 0.98 | TACR1 (0.69) | TACR1 | |
| SCHEMBL6299711 | 0.90 | TACR1 (0.70) | TACR1 | |
| SCHEMBL7035504 | 0.90 | TACR1 (0.63) | TACR1 | |
| SCHEMBL6947598 | 0.89 | TACR1 (0.74) | TACR1 | |
| SCHEMBL6763282 | 0.88 | TACR1 (0.71) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729468-B1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2003-01-15 | — | — | EP | claimed |
| US-6239144-B1 | ADMINISTERING A TACHYKININ RECEPTOR ANTAGONIST, 2-(N-(2-((4-CYCDOHEXYL)PIPERAZIN-1-YL)ACETYL)AMINO)-3-(1H-INDO L-3-YL)-1-(N-(2-METHOXYBENZYL)ACETYLAMINO)PROPANE, | ELI LILLY AND COMPANY | 2001-05-29 | — | — | US | claimed |
| JP-2000511193-A | — | — | 2000-08-29 | — | — | JP | claimed |
| EP-0912178-A4 | METHODS OF TREATING HYPERTENSION | LILLY CO ELI (US) | 2000-08-16 | — | — | EP | claimed |
| US-6017930-A | Methods of treating or preventing interstitial cystitis | ELI LILLY AND COMPANY (US) | 2000-01-25 | — | — | US | claimed |
| US-6001837-A | Methods of treating or preventing sleep apnea | ELI LILLY AND COMPANY (US) | 1999-12-14 | — | — | US | claimed |
| EP-0912178-A1 | METHODS OF TREATING HYPERTENSION | ELI LILLY AND COMPANY (US) | 1999-05-06 | — | — | EP | claimed |
| EP-0710479-B1 | Use of a serotonin agonist in combination with a tachykinin receptor antagonist for the manufacture of a medicament for the treatment or prevention of migraine | LILLY CO ELI (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1998043639-A1 | METHODS OF TREATING BONE LOSS | ELI LILLY AND COMPANY (US) | 1998-10-08 | — | — | WO | claimed |
| WO-1997044035-A1 | METHODS OF TREATING HYPERTENSION | ELI LILLY AND COMPANY (US) | 1997-11-27 | — | — | WO | claimed |
| WO-1997007117-A1 | 2-ACYLAMINOPROPANAMINES AS GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1997-02-27 | — | — | WO | claimed |
| WO-1996041633-A1 | METHODS OF TREATING COLD AND ALLERGIC RHINITIS | ELI LILLY AND COMPANY (US) | 1996-12-27 | — | — | WO | claimed |
| EP-0747055-A2 | Use of tachykinin receptors antagonists for the treatment of cold and allergic rhinitis | ELI LILLY AND COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| EP-0747049-A1 | Use of tachykinin antagonists in combination with serotonin agonists or serotonin reuptake inhibitors for the manufacture of a medicament for the treatment of allergic rhinitis | ELI LILLY AND COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| WO-1996029074-A1 | METHODS OF TREATING OR PREVENTING PAIN OR NOCICEPTION | ELI LILLY AND COMPANY (US) | 1996-09-26 | — | — | WO | claimed |
| EP-0729468-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0729468-A4 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1996-07-12 | — | — | EP | claimed |
| EP-0710479-A1 | Use of a serotonin agonist in combination with a tachykinin receptor antagonist for the manufacture of a medicament for the treatment or prevention of migraine | ELI LILLY AND COMPANY (US) | 1996-05-08 | — | — | EP | claimed |
| WO-1996011000-A1 | METHODS OF TREATING MIGRAINE | ELI LILLY AND COMPANY (US) | 1996-04-18 | — | — | WO | claimed |
| WO-1995014017-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1995-05-26 | — | — | WO | claimed |