⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470869 | 0.81 | — | — | |
| SCHEMBL7286681 | 0.78 | — | — | |
| SCHEMBL2402865 | 0.72 | — | — | |
| SCHEMBL928138 | 0.72 | — | — | |
| SCHEMBL30416905 | 0.72 | — | — | |
| SCHEMBL82591 | 0.72 | — | — | |
| SCHEMBL7156618 | 0.71 | — | — | |
| SCHEMBL4054231 | 0.67 | — | — | |
| SCHEMBL8326033 | 0.67 | — | — | |
| SCHEMBL10949948 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184764-A1 | CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| EP-0532767-B1 | 3-Phenoxybenzyl(idene)pyrrolidine derivatives, their preparation and their use as muscarinic cholinergic agents | KANEGAFUCHI CHEMICAL IND (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5270339-A | Phenoxybenzene derivative | KANAGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0532767-A1 | 3-Phenoxybenzyl(idene)pyrrolidine derivatives, their preparation and their use as muscarinic cholinergic agents | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-03-24 | — | — | EP | disclosed |