SCHEMBL29977859

SCHEMBL29977859

CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CS)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 9/20 0.58
NAALAD2 Q9Y3Q0 1/20 0.47
BMP1 P13497 1/20 0.46
MME P08473 2/20 0.45
ALDH1A1 P00352 1/20 0.44
BACE1 P56817 2/20 0.44
BACE2 Q9Y5Z0 1/20 0.44
DPP4 P27487 1/20 0.43
DPP8 Q6V1X1 1/20 0.43
DPP9 Q86TI2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29893864 1.00 FOLH1 (0.58) FOLH1NAALAD2BMP1MMEALDH1A1
SCHEMBL29892709 0.95 FOLH1 (0.53) FOLH1BACE1
SCHEMBL31097671 0.95 FOLH1 (0.52) FOLH1BMP1BACE1BACE2
SCHEMBL31097664 0.95 FOLH1 (0.52) FOLH1BMP1BACE1BACE2
SCHEMBL31097672 0.95 FOLH1 (0.52) FOLH1BMP1BACE1BACE2
SCHEMBL31097707 0.95 FOLH1 (0.52) FOLH1BMP1BACE1BACE2
SCHEMBL31097688 0.92 FOLH1 (0.53) FOLH1NAALAD2BMP1BACE1BACE2
SCHEMBL31097708 0.92 FOLH1 (0.53) FOLH1NAALAD2BMP1BACE1BACE2
SCHEMBL31097687 0.92 FOLH1 (0.53) FOLH1NAALAD2BMP1BACE1BACE2
SCHEMBL30527800 0.92 FOLH1 (0.53) FOLH1NAALAD2BMP1BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12129277-B2 Linear solution phase routes for WNT hexapeptides WNTRESEARCH AB (SE) 2024-10-29 US disclosed
CN-112638934-B Solution phase Path for WNT hexapeptide 温特研究公司 2024-06-11 CN disclosed
US-11970551-B2 Solution phase routes for WNT hexapeptides WNTRESEARCH AB (SE) 2024-04-30 US disclosed
CN-113646324-B Linear solution phase pathway for WNT hexapeptide 温特研究公司 2024-03-29 CN disclosed
US-11912791-B2 Solution phase routes for Wnt hexapeptides WNTRESEARCH AB (SE) 2024-02-27 US disclosed
US-20230295232-A1 SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES WNTRESEARCH AB (SE) 2023-09-21 US disclosed
EP-3841107-B1 SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES WNTRESEARCH AB (SE) 2023-06-28 EP disclosed
EP-3894426-B1 LINEAR SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES WNTRESEARCH AB (SE) 2022-09-21 EP disclosed