Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 7/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978077 | 0.92 | HDAC4 (0.53) | HDAC4HDAC6HDAC8HDAC1BRD4 | |
| SCHEMBL29978185 | 0.89 | HDAC6 (0.42) | HDAC4HDAC6HDAC8HDAC1HDAC2 | |
| SCHEMBL29978352 | 0.87 | HDAC4 (0.44) | HDAC4HDAC6HDAC8HDAC1HDAC2 | |
| SCHEMBL29977956 | 0.85 | HDAC4 (0.42) | HDAC4HDAC6HDAC8HDAC1ESR2 | |
| SCHEMBL29978903 | 0.84 | HDAC4 (0.40) | HDAC4HDAC6HDAC8HDAC1HDAC2 | |
| SCHEMBL29978854 | 0.84 | HDAC4 (0.42) | HDAC4HDAC6HDAC8HDAC1HDAC2 | |
| SCHEMBL29978178 | 0.84 | HDAC4 (0.42) | HDAC4HDAC6HDAC8HDAC1HDAC2 | |
| SCHEMBL29978564 | 0.84 | HDAC4 (0.41) | HDAC4HDAC6HDAC8HDAC1HDAC2 | |
| SCHEMBL29978705 | 0.83 | HDAC4 (0.47) | HDAC4HDAC6HDAC8HDAC1HDAC2 | |
| SCHEMBL29978150 | 0.83 | HDAC4 (0.45) | HDAC4HDAC6HDAC8HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |