Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BRS3 | P32247 | 9/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978503 | 0.91 | HDAC6 (0.47) | HDAC6HDAC4BRS3HDAC8HDAC1 | |
| SCHEMBL29978732 | 0.91 | HDAC4 (0.55) | HDAC6HDAC4BRS3HDAC8HDAC1 | |
| SCHEMBL29978371 | 0.91 | HDAC4 (0.52) | HDAC6HDAC4BRS3HDAC8HDAC1 | |
| SCHEMBL29978148 | 0.89 | HDAC4 (0.51) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29977787 | 0.87 | HDAC6 (0.50) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29978176 | 0.86 | GRM5 (0.45) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29978027 | 0.86 | HDAC6 (0.53) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29978080 | 0.86 | HDAC4 (0.53) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29978622 | 0.86 | HDAC6 (0.53) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29978189 | 0.85 | HDAC6 (0.52) | HDAC6HDAC4HDAC8HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |