Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 9/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978108 | 0.93 | HDAC4 (0.40) | HDAC4HDAC6HDAC8HDAC2MAPT | |
| SCHEMBL29979110 | 0.92 | HDAC4 (0.39) | HDAC4HDAC6HDAC8HDAC2BRD4 | |
| SCHEMBL29978536 | 0.90 | HDAC4 (0.49) | HDAC4HDAC6HDAC8HDAC2MAPT | |
| SCHEMBL29978968 | 0.88 | HDAC4 (0.42) | HDAC4HDAC6HDAC8HDAC2BRD4 | |
| SCHEMBL29978569 | 0.87 | HDAC4 (0.52) | HDAC4HDAC6HDAC8HDAC2MAPT | |
| SCHEMBL29978900 | 0.87 | NPC1 (0.48) | MAPTNPC1LMNAALDH1A1TSHR | |
| SCHEMBL29978903 | 0.86 | HDAC4 (0.40) | HDAC4HDAC6HDAC8HDAC2MAPT | |
| SCHEMBL29978373 | 0.85 | HDAC4 (0.39) | HDAC4HDAC6HDAC8HDAC2LIPE | |
| SCHEMBL29978506 | 0.84 | HDAC6 (0.42) | HDAC4HDAC6HDAC8HDAC2MAPT | |
| SCHEMBL29978077 | 0.84 | HDAC4 (0.53) | HDAC4HDAC6HDAC8HDAC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |