Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 20/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067085 | 0.86 | EPHX2 (0.75) | EPHX2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29979075 | 0.86 | EPHX2 (0.75) | EPHX2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29978791 | 0.86 | EPHX2 (0.78) | EPHX2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29067096 | 0.85 | EPHX2 (0.82) | EPHX2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29978592 | 0.85 | EPHX2 (0.82) | EPHX2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL28431225 | 0.83 | EPHX2 (1.00) | EPHX2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29979081 | 0.83 | EPHX2 (0.82) | EPHX2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29978744 | 0.83 | EPHX2 (0.72) | EPHX2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL29978731 | 0.82 | EPHX2 (0.78) | EPHX2 | |
| SCHEMBL29067090 | 0.82 | EPHX2 (0.78) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022227743-A1 | MEMANTINE UREA DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 沈阳药科大学 | 2022-11-03 | — | — | WO | claimed |
| WO-2022227743-A1 | MEMANTINE UREA DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 沈阳药科大学 | 2022-11-03 | — | — | WO | disclosed |