Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.77 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978843 | 1.00 | EPHX2 (0.77) | EPHX2GLAHSD17B10 | |
| SCHEMBL29979386 | 1.00 | EPHX2 (0.77) | EPHX2GLAHSD17B10 | |
| SCHEMBL29979184 | 0.92 | EPHX2 (0.79) | EPHX2 | |
| SCHEMBL29979695 | 0.92 | EPHX2 (0.79) | EPHX2 | |
| SCHEMBL29979043 | 0.90 | EPHX2 (0.76) | EPHX2 | |
| SCHEMBL29978519 | 0.90 | EPHX2 (0.81) | EPHX2 | |
| SCHEMBL29979896 | 0.90 | EPHX2 (0.76) | EPHX2 | |
| SCHEMBL29979044 | 0.90 | EPHX2 (0.72) | EPHX2 | |
| SCHEMBL29978809 | 0.89 | EPHX2 (0.75) | EPHX2 | |
| SCHEMBL30570991 | 0.89 | EPHX2 (0.76) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022227743-A1 | MEMANTINE UREA DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 沈阳药科大学 | 2022-11-03 | — | — | WO | claimed |
| CN-113185451-B | Memantine urea derivative, and preparation method and application thereof | 沈阳药科大学 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022227743-A1 | MEMANTINE UREA DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 沈阳药科大学 | 2022-11-03 | — | — | WO | disclosed |