Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 13/20 | 0.76 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21272048 | 0.89 | CHRM1 (0.78) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL21272050 | 0.89 | CHRM1 (0.78) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL25411916 | 0.88 | CHRM1 (0.63) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL25411923 | 0.88 | CHRM1 (0.63) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL25411919 | 0.88 | CHRM1 (0.63) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL31366492 | 0.88 | CHRM1 (0.63) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL25411165 | 0.87 | CHRM1 (0.61) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL31366540 | 0.87 | CHRM1 (0.61) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL25411158 | 0.87 | CHRM1 (0.61) | CHRM1GABRA1GABRA5GABRA3GABRA2 | |
| SCHEMBL21272219 | 0.86 | CHRM1 (1.00) | CHRM1CCKBRMEN1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403478-B | Preparation method of N- (2-benzoylphenyl) -2-trifluoroacetamido alkylamide derivative | 温州医科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-115403478-A | Preparation method of N- (2-benzoylphenyl) -2-trifluoroacetylaminoalkanamide derivative | 温州医科大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-115322160-A | Preparation method of 5-aryl-1,4-benzodiazepine-2-one compound | 温州医科大学 | 2022-11-11 | — | — | CN | disclosed |