Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 6/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117270 | 1.00 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1CDK2METAP2 | |
| SCHEMBL20407296 | 0.81 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1METAP2 | |
| Hydrochloric Acid SCHEMBL29979565 | 0.79 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL26907832 | 0.79 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10228470 | 0.77 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1CDK2LMNA | |
| SCHEMBL14617215 | 0.77 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1CDK2LMNA | |
| SCHEMBL17011560 | 0.77 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1CDK2 | |
| SCHEMBL29117192 | 0.76 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29979784 | 0.76 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14617224 | 0.74 | SLC1A3 (0.40) | SLC1A3SLC1A2SLC1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284365-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| CN-117177744-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022165513-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-08-04 | — | — | WO | disclosed |