Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.49 |
| ▸ | PRNP | P04156 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20338474 | 1.00 | RXFP1 (0.49) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL29177611 | 0.82 | RXFP1 (0.60) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28220202 | 0.79 | RXFP1 (0.57) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL1061506 | 0.76 | RXFP1 (0.50) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL29980697 | 0.76 | MAOB (0.51) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL19810854 | 0.76 | MAOB (0.51) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL11189080 | 0.72 | RXFP1 (0.60) | RXFP1PRNPKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL12795599 | 0.71 | PRNP (0.61) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL11029724 | 0.71 | PRNP (0.59) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL8347789 | 0.71 | PRNP (0.59) | RXFP1PRNPKDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11464770-B2 | Anticancer pharmaceutical composition | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2022-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11464770-B2 | Anticancer pharmaceutical composition | MYC, MYCBP, TP53 | RXFP1 4869/4885PRNP 1647/4885KDM4E 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.